Artesiane suppogel

Active substance: artemether

Form: rectal capsules – suppogels

Dosage: 40 mg/ suppogel

Packaging: Box with 1 blister of 6 suppogels

Target : children (6months – 3 y)

Artesiane suppogel is indicated for

• The treatment of malaria caused by all forms of Plasmodium, including the most resistant strains.
• is specifically indicated in the treatment of severe malaria and in pre-transfer treatment.
• In the treatment of simple forms of malaria Artesiane Suppogel can be used in case applying an oral form is difficult or impossible.

Treatment of acute malaria attacks due to Plasmodium falciparum. Rectal

capsules /suppogels are intended for emergency treatment, at a time when the

administration of other forms is difficult or impossible. This medication is available to mothers to treat their adolescents in the absence of medical help.

This presentation applies in particular to rural areas of developing countries.

According to the recommendations, a monotherapy treatment with Artesiane Suppogel should be followed by a complete cure with an effective oral CTA.

Artesiane Suppogel is specifically indicated in the pre-transfer treatment of severe malaria. In the case of a suspected severe malaria, and when the time between the transfer of the patient to the care unit and the start of treatment is more than 6 hours, pre-transfer treatment is recommended. If a transfer is impossible the treatment should take its course until the patient is able to take oral treatment and complete a cure with an effective CTA.

The dose depends on the severity of the case and the clinical state of the patient.

Starting dose: 4 mg/kg bodyweight on the first day

Following days: Dose of 2mg/kg bodyweight from day 2 off.

Rectal capsules (suppogels) are generally administered to children and adolescent and to elderly having difficulties of swallowing oral forms, or having gastro-intestinal problems, as well as in severe cases such as neuromalaria, with decreased consciousness or in the event of a coma. When the patient regains consciousness or, in the absence of gastrointestinal problems, treatment will be followed by oral treatment with an effective CTA.

Rectal administration. The capsule is inserted in the anus and pushed into the rectum. In case needed, the patient is kept lying down avoiding that the capsule is pushed out.